So a Simpsons character will come out of the closet in the not too distant future. I doubt it'll be Smithers because his sexuality is hardly a secret. So that narrows it down to...
Homer/Marge/Bart/Lisa/Grandpa Simpson, Selma, Patty, Herb Powell, Ned/Rod/Todd Flanders, Kirk/Luann/Milhouse Van Houten, Apu/Manjula Nahasapeemapetilon, Chief/Sarah/Ralph Wiggum, Dr Hibbert, Reverend/Helen Lovejoy, Cletus, Mr Burns, Lenny, Carl, Charlie, Principal Skinner, Superintendent Chalmers, Ms Krabappel, Miss Hoover, Mr Largo, Willie, Doris the lunchlady, Dr Pryor (psychiatrist), Otto Mann, Nelson Muntz, Jimbo, Dolph, Kearney, Martin Prince, Wendell, 'The school nerds', Louis, Janie, Sherrie and Terrie, Uter, Mayor Quimby, Lou, Eddie, Lionel Hutz, Snake, Fat Tony, Krusty the Klown, Sideshow Bob, Sideshow Mel, Kent Brockman, Arnie Pie, Bumblebee Man, Roger Meyers, Troy McClure, Rainer Wolfcastle, Moe, Barney, Dr Nick Riviera, Comic Book guy, Disco Stu, Duffman, Hans Moleman, Jasper and Herman the military antiques store owner.
I guess you can chuck in Kang and Kodos for good measure.
Who do you think?